chromium toxicity from hip replacement symptoms and treatmentchrome repair

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Cobalt poisoning Information | Mount Sinai

Cobalt poisoning can also occur from the wear and tear of some cobalt/chromium metal-on-metal hip implants. This type of implant is an artificial hip socket that is created by fitting a metal ball into a metal cup. Sometimes, metal particles (cobalt) are released as the metal ball grinds against the metal cup when you walk.

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Chromium toxicity: Causes, complications, treatment, & safety

Symptoms of chromium toxicity. Heavy exposure to chromium (IV) has been reported to cause the following debilitating symptoms in individuals working in such hazardous conditions: Acute dermatitis and skin ulcers (also known as chrome ulcers). Respiratory complications such as bronchitis and asthma. Sinusitis and perforations in …

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Immune Response to Implants and Biomaterials

Markel et al reported the use of a dual-mobility cobalt-chromium hip replacement prosthesis with which metal ion levels were undetectable or minimal after 1-2 years; in addition, percentages of B cells and T cells were normal, with no increase in CD16 inflammatory monocytes, indicating the absence of an immune response to the implant.

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Cobalt Toxicity Complication of Hip Replacement Surgery

Three different case studies of cobalt toxicity after hip replacement surgery were presented within 10 days of each other in early 2014. The remarkable nature of these case studies is that "hip pain was not a prominent feature," Dr. Bunning says. The patients did present with similar symptoms, and all were found to have excessively high ...

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Metal on Metal Hips Linked to Dementia and Depression

Title: "Neuropsychiatric symptoms following metal-on-metal implant failure with cobalt and chromium toxicity" Abstract. Many metal-on-metal (MoM) total hip replacement implants have been recalled due to high failure rates. This study assesses the mental health of 10 patients who underwent revision surgery for failed MoM implants.

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Neuropsychiatric symptoms following metal-on-metal implant …

Background There were at least 31,171 metal-on-metal (MoM) hip implants in the UK between 2003 and 2011. Some of these were subject to failure and widescale recalls and revisions followed. Method This is a presentation of ten cases (mean age 60 years) where we evaluated neuropsychiatric morbidity following metal-on-metal hip implant …

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Metal-on-Metal Hip Joint Prostheses: a Retrospective Case

Introduction: There have been concerns about prosthesis failure and the potential for systemic toxicity due to release of cobalt and chromium from metal-on-metal hip joint …

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Metal-on-Metal Hip Joint Prostheses: a Retrospective Case

Introduction: There have been concerns about prosthesis failure and the potential for systemic toxicity due to release of cobalt and chromium from metal-on-metal hip joint prostheses (MoM-HP). There is conflicting evidence on whether there is a correlation between higher cobalt and chromium concentrations and systemic toxicity.

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Cobalt Poisoning From Hip Replacements: A Real Danger

Cobalt poisoning can cause a wide range of symptoms, including problems with the hips and joints. In some cases, it can lead to hip replacement surgery. Symptoms can also include fatigue, headaches, dizziness, and mood changes. In severe cases, cobalt poisoning can cause heart problems and even death.

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Metal Hypersensitivity

Metal hypersensitivity is a disorder of the immune system. It is a common condition that affects 10% to 15% of the population. It can produce a variety of symptoms, including rashes, swelling, or pain due to contact with certain metals (see the symptoms and complications section, below). In addition to the local skin reactions, metal ...

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Why Cobalt Chrome Is A Good Choice For Medical Implants

Anyone who has a metal-on-metal hip replacement is at risk of Cobalt-Chromium poisoning. When a patient is wearing a metal hip replacement, the metal level in their urine is normal. DePuy orthopedics Inc. has found high levels of cobalt and/or chromium in its products. Defective hip replacement surgeries can result in serious …

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Cobalt-Induced Toxicity and Spasticity Secondary to Hip Arthroplasty

Case presentation. A 45-year-old male presented to our institution for evaluation and treatment of severe generalized spasticity. His past medical history was significant for right hip arthroplasty with a cobalt-chrome implant in 2010, left hip arthroplasty with a cobalt-chrome implant in 2011, and relapsing-remitting multiple …

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What Are The Effects Of Chromium Poisoning?

Symptoms of Chromium Poisoning. The symptoms vary depending on the form of contact with chromium. Exposure could happen through the mouth, excessive inhalation, or through the skin after …

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Chromium (Cr) Toxicity: Where Is Chromium Found?

The general population is exposed to chromium by eating food or food supplements, drinking water, and inhaling air that contain chromium. The mean daily dietary intake of chromium from air, water, and food is estimated to be <0.2-0.4, 2.0, and 60 micrograms, respectively [ATSDR 2000]. One study found increased blood chromium level after total ...

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Chromium and Cobalt

The FDA recommends that orthopedic surgeons measure chromium and cobalt in metal-on-metal hip implant in patients with symptoms of this adverse reaction. …

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Symptoms of cobalt poisoning? | Mayo Clinic Connect

A measure of 5.6 is considered "borderline" by some docs, but it becomes and issue if you are having symptoms. Cobalt poisoning can lead to very serious health issues over time, and can also cause the implant to fail, leaving enough damage to bone, muscle & tendons to make revision difficult.

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Final Diagnosis -- Case 806

Total hip replacement using implantable metal components is a common medical surgery that has been performed in North America for more than 50 years. ... recommends following patients with cobalt alloy-containing metal-on-metal hip prostheses for cobalt toxicity symptoms at least annually for five years post-implantation[1]. ... Zwelmueller, et ...

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Systemic Effects of Metals Released from Arthroplasty Implants

The toxic potential of chromium is considered less pronounced. Yet, in arthroplasty there is usually a co-exposure to chromium and cobalt which complicates evaluation of element-specific effects. ... Release of further metals such as tantalum, niobium, nickel, vanadium and zirconium from hip and knee replacement implants has …

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Concerns about Metal-on-Metal Hip Implants | FDA

Metal-on-metal (MoM) hip implants have unique risks in addition to the general risks of all hip implants. In MoM hip implants, the metal ball and the metal cup slide against each …

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10 Million People with Hip, Knee and Shoulder Replacements Are …

Metals poisoning is called metallosis. Both chromium and cobalt are metals that, over time, can poison an individual who has too much of them built up in his or her body. They can cause damage to the respiratory system, the kidneys and the heart. In particular, cobalt poisoning can lead to: Cardiomyopathy. Deafness.

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Chromium and cobalt intoxication mimicking mitochondriopathy

A 53-year old male with a history of progressive visual impairment, hearing loss, peripheral neuropathy, poorly controlled diabetes mellitus, cardiomyopathy, and weight loss was referred to the rare disease center due to the suspicion of mitochondrial cytopathy. In line with mitochondrial dysfunction, lactate in CSF was increased. Genetic testing by …

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Cardiac transplant due to metal toxicity associated with hip

Concerns regarding metal-on-metal (MoM) bearing couples in total hip arthroplasty are well documented in the literature with cobalt (Co) and chromium (Cr) toxicity causing a range of both local and systemic adverse reactions. We describe the case of a patient undergoing cardiac transplantation as a direct result of Co and Cr …

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The effects on bone cells of metal ions released from orthopaedic

The effects of metal particles on bone cells and bone resorption is a crucial issue for orthopaedic implant durability. In orthopaedic implants, the most frequent manifestation of local osteolysis is reported with hip arthroplasties. The knee seems to be less vulnerable, but it is unclear why.

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Current Concerns with Metal-on-Metal Hip Arthroplasty

all hint of joint sepsis. Other symptoms such as a feeling of swelling or fullness about the hip, and mechanical symptoms of crepitus, clicking or squeaking should be elicited. A clinical history of metal allergy manifested as a dermal reaction to metal jewelry may also be helpful in assessing potential hypersensitivity reactions.

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Hearing Loss Tinnitus and Metal Hip Replacement Lawsuits

If you experience any of the following symptoms in one or both ears, your metal-on-metal hip implant may be the cause: Inability to hear higher-pitched sounds. For example, you may have difficulty understanding or hearing words with "S," "H," and "F" sounds. Difficulty understanding female voices more than male voices. Trouble with ...

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Cobalt hip prosthesis intoxication mimicking an autoimmune disease

Highlights. Cobalt-containing hip prosthesis may cause systemic toxicity due to the release of cobalt from metal-on-metal (MoM) joint arthroplasty into the bloodstream. High cobalt blood levels can lead to a variety of clinical manifestations, mimicking other disorders, especially autoimmune, hematologic, and infectious diseases.

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I received 2 hip replacements and then developed cobalt

I am one of thousands that received 2 hip replacements and then developed cobalt & chromium and had to have them both again replaced-I need a brain MRI. If I …

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Metal Allergy to Surgical Plates, Screws, and Implants …

Metals Used. Reactions. Removal. Having a metal allergy or sensitivity doesn't mean getting a metal implant like a surgical screw, plate, or joint replacement is entirely off limits or that the body will reject it. But …

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Chromium

A small study in eight men and 11 women in the United States found mean chromium intakes of about 29 mcg/day for women and 54 mcg/day for men [ 30 ]. In another study, the mean chromium content per 2,000 kcal of 22 well-balanced diets designed by nutritionists was about 27 mcg and ranged from about 17 to 47 mcg [ 17 ].

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Dementia and Metal on Metal Hip RePlacements

Metal on metal hip replacements can release high levels of metal particles like cobalt and chromium into a patient's body. This happens when the metal surfaces of the cup and ball rub together and flake off tiny metal ions that travel through the body in the bloodstream causing metal poisoning. Dementia can be one of the side effects of metal ...

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